Endocrine Abstracts

Introduction: Type 1 diabetes is accompanied by a high frequency of autoimmune diseases.The aim: of this study is to determine the different epidemiological, clinical, immunological and therapeutic aspects of Type 1 Diabetes in Autoimmune Polyendocrinopathy and to analyze the results obtained.Patients and methods: This is a retrospective study of 44 patients with type 1 diabetes, suffering from Autoimmune Polyendocrinopathy and fol...

Introduction: Compared to normal population, patients with neurofibromatosis are at higher risk for the development of benign and malignant tumors. Pheochromocytomas are relatively rare in neurofibromatosis type 1 (NF1), and malignant ones are even rarer.Aim of the presentation: Our aim was to report a malignant pheochromocytoma with multiple metastases in a patient with NF1.Case report: A male patient aged 23 years old, with lapar...

Introduction: Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor that arises from the parafollicular C-cells of the thyroid gland with a tendency to regional and distant metastases. It is a rare tumor, making up about 3% of all thyroid malignancies. MTC occurs in both heritable and sporadic forms, early diagnosis is important as it can improve treatment outcomes. We report a case of metastatic medullary thyroid cancer with both diagnostic and therapeutic challenges. <...

Hypoglycemia in non-diabetic patients is a rare event, and autoimmune hypoglycemia with the presence of positive anti-insulin antibodies is even rarer.We report the case of a 15 years old non diabetic female patient, she was referred to our hospital for recurrent hypoglycemia for 2 weeks before admission to hospital, these are severe hypoglycemia with impaired consciousness. The first step was to eliminate the general causes and factitious hypoglycemia. ...

Introduction: Pituitary adenomas are a rare condition in children and young people. The prolactinoma represents the most frequent of them. We report a case of an atypically evolution of aggressive macroprolactinoma in young patient.Case: It’s about a boy of 14 years old with previous history of headache from 5 years without visual disturbance. He was admitted for intracranial hypertension syndrome. In clinical examination no dysmorphic syndrome, a g...

Introduction: Clinically non-secreting pituitary adenomas are rare in children We report a case of a silent somatotropic adenoma revealed by anatomopathology.Case: A 13 year-old patient with no prior history of sudden onset intracranial hypertension syndrome. Clinical examination showed no dysmorphic Syndrome, no galactorrhea, no delay or statutory advance, Tanner P1S3. The MRI reveals a heterogeneous tumor process intra and suprasellar of 30 mm *15 mm o...

Introduction: Pituitary adenomas are rare in infants and adolescents. Prolactinomas account for 50% of these pituitary adenomas. In adolescent girls, it is usually a microprolactinoma revealed by puberty delay or amenorrhea. We report a rare case of a macroprolactinoma in an adolescent girl revealed by visual impairment.Case presentation: A 15-year-old adolescent girl presented with loss of vision over a long period of time. Magnetic resonance imaging re...

Introducing: Hypothyroidism is the most common endocrinopathy causing rhabdomyolysis. Muscle manifestations are common in hypothyroidism, but myopathy is most often limited to discrete clinical signs such as myalgias, stiffness or cramps accompanied by a simple elevation of muscle enzymes. On the other hand, rhabdomyolysis associated with hypothyroidism is a rare diagnosis to our knowledge. We report a case of severe rhabdomyolysis in the setting of profound Hashimoto’s h...

Graves’ disease is a rare and severe disease that most often affects older children and is predominantly female. The diagnosis is made in the presence of a clinical picture very suggestive of thyrotoxicosis, confirmed by biological and radiological tests. We present the case of an 11-year-old female patient who presented with a moderate presented of basedow with an ultrasound appearance of thyroiditis for which scintigraphy was helpful in the diagnosis. Female patient, 11...

Introduction: The association of multi-organ autoimmune disorders is described. We report a case of Hashimoto’s thyroiditis (HT) and primary biliary cholangitis (PBC), both are a chronic autoimmune inflammation, with lymphocytic infiltration and destruction of thyroid cells for (HT) and progressive destruction of intrahepatic bile ducts leading to cirrhosis for (PBC)Case report: 54-year-old female patient, followed for (PBC) at cirrhosis stage admit...